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Lab assembly with the Blood Engineering Lab

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Lab assembly with the Blood Engineering Lab

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Lab web site: The Blood Engineering Lab (riosugimura.com)

The place is the lab?

Hong Kong

Analysis abstract

Rio: We work on the intersection of bioengineering, immunology, and stem cell know-how to invent new instruments for understanding and treating cancers. The mission of The Blood Engineering Lab (BEL) is to outline elementary rules of anti-cancer immune cells and apply these insights towards bettering chimeric antigen receptor (CAR) know-how and checkpoint immunotherapy. We apply cutting-edge approaches together with single-cell RNA sequencing, molecular barcoding, organoids, and stem cell differentiation. The objective is to invent new instruments for understanding and treating cancers.  

Are you able to give us a lab roll name?

Yiming: PhD Candidate. Computational biologist in coaching at Cambridge College. She is a wizard of single-cell and spatial information evaluation.

Sanxing: PhD Candidate. Tissue tradition veteran. Can’t consider any cell sort he can not tradition. Changing into an artificial immunologist.

David: PhD Candidate. Chromium, Visium, Multiomics… He turned a guru of 10X Genomics methods. Organs-on-chips and myeloid checkpoint.

Shihui: PhD Candidate. One other computational wizard of BEL. Machine-learning to foretell cell destiny.

Sophronia: Grasp scholar main a global group inside a lab. CAR-macrophages from human pluripotent stem cells.

Alex: Grasp scholar. Finding out myeloid checkpoint in assembloids.

Daniel: Visiting postdoc. Professional in AAV and gene modifying.

Theo: Visiting medical scholar from Heidelberg, Germany. Making Tremendous-CAR.

Patrick: Visiting PhD Candidate from Pavia, Italy. Professional in antibody engineering.

The Sugimura Lab

Favorite method, and why?

Rio: I grew up with move cytometry. Nonetheless watching FACS plots is probably the most FAVE time of mine. Used to complete my postdoc day having fun with drinks at my go-to bar with catch-of-the-day FACS plots (I needed to cease this nerd behavior after having infants…). Now I’m shifting my dependancy to single-cell information.

Aside from your personal analysis, what are you most enthusiastic about in developmental and stem cell biology?

Rio: Engineering stem cell biology. Reconstruction and the endowment of latest operate.

How do you method managing your group and all of the totally different duties required in your job?

Rio: I’ve two labs. It’s an additional problem in addition to pleasure. I put most of my effort into two labs speaking easily. I shuttle myself between two labs. Very busy, however sitting down with college students and discussing information is a rewarding a part of my job. Zoom and Slack are nice. I can not think about how I might function my labs with out these. Moreover labs, I at all times spot myself in a grant-writing seat, specifically Starbucks, Pacific Espresso, and Espresso Lecturers.

What’s the smartest thing about the place you’re employed? 

Yiming: The lab is at all times encouraging information trade and collaboration inside and out of doors Hong Kong. Everybody has numerous probabilities to speak to different folks and get suggestions on the tasks. These are essential for junior college students to learn to do analysis.

Sanxing: I feel our lab combines many alternative instructions and is a giant fan of collaboration, which evokes me lots.

David: I’m very fortunate to be in Dr. Rio’s lab as a consequence of my sturdy reference to numerous specialists in several labs. I benefit from the FACS machine, BioRad PCR & qPCR machine in addition to the companies offered by the HKU-Med leaders, and technicians.

Alex: At HKU, the supportive tradition encourages shared insights and vibrant discussions about grand theories and passions. Being a part of this huge establishment promotes mental cross-pollination with different labs, and the plethora of free seminars and lectures additional bolsters our educational development.

Sophronia: I just like the collaborative tradition probably the most in our lab. We don’t resolve issues alone, we resolve issues collectively. We additionally have interaction with folks from totally different labs with totally different experience, and that’s how we provide you with new concepts.

Theo: Working at Hong Kong College’s BEL analysis laboratory is an incredible expertise. The lab is a superb surroundings for analysis, and Rio is without doubt one of the greatest PIs I’ve labored – academically, and in addition personally. The analysis matter is fascinating, and our collaborative tasks are thrilling. Nevertheless, the very best factor about working on the BEL is the excellent environment with my co-workers. Everyone seems to be pleasant and supportive, making it an important place to work. The lab’s tradition of collaboration and teamwork is what makes it stand out from different analysis labs. It’s inspiring to see how everybody works collectively to realize frequent objectives and the way everyone seems to be prepared to assist one another out. Moreover, the lab’s location in Hong Kong is a superb benefit, because it offers entry to a various vary of sources and alternatives for analysis and collaboration. Total, working on the BEL has been an unbelievable expertise, and I really feel lucky to be a part of such a dynamic and supportive analysis group.

Patrick: 1) The lab’s dedication to groundbreaking science. That is wonderful from the perspective of the challenges inherent to translational stem cell biology and it’s relevance to most cancers therapies 2) Common conferences. The weekly science conferences to my opinion is a vital second to debate and share concepts, factors of view and techniques about totally different experiments. This enforces the conception and science methodologies to totally different experimental protocols, and permits for a stable basis of the lab’s self-approach in tackling issues 3) The in depth community of collaborations, worldwide seminars, conferences and conferences, to which lab members often participate.

What’s there to do exterior of the lab?

Yiming: Limitless mountain and sea!

Sanxing: Hong Kong is a superb metropolis. There are many mountain climbing mountains equivalent to Dragon’s Again, Sundown Peak, and Victoria Peak surrounded by stunning seas and stress-free landscapes. We normally go mountain climbing or swimming to have enjoyable on the weekend

David: I benefit from the corridor life, for instance, becoming a member of Spartan Working, Excessive Desk Dinner, and K11 MUSEA with tutors/masters. Now, I, along with an engineering good friend, lead the mountain climbing membership within the Jockey Membership Scholar Village III. As a captain of the membership, I can’t solely expertise lots of good sea views but additionally meet new buddies right here.

Sophronia: Hong Kong is a meals paradise, so tasting meals would undoubtedly be probably the greatest factor to do. The night time life in Hong Kong can also be very nice the place you may hang around with buddies, go seize a drink, meet new buddies and socialize.

Alex: Outdoors the lab, Hong Kong presents an abundance of actions. Prime amongst these is mountain climbing, with the town’s assorted landscapes providing all the pieces from rugged peaks to tranquil seashores. Moreover, the School of Medication homes a close-by swimming pool, an everyday hang-out of mine. Each present wonderful avenues for unwinding after intense lab classes.

Theo: Dwelling in Hong Kong is an expertise like no different. The town is an ideal mix of chaos and colour, making it a incredible place to dwell. First, the town is surrounded by nature, with many outlying islands, nation parks, and mountain climbing trails. So, there’s at all times one thing new to discover. Second, the meals right here is wonderful, with all the pieces from dim sum to noodle outlets to oven-baked pizza. Third and final, the skyline and the town vibe are breathtaking. The view from The Peak is without doubt one of the most iconic on this planet, and from festivals to cultural landmarks, there’s at all times one thing to see and do. Total, whether or not you’re a nature lover, a foodie, or a tradition fanatic, there’s at all times one thing new to find on this vibrant metropolis.

Patrick: Hong Kong is an incredible Metropolis, with stunning landscapes, and plenty of locations to go to. There are at all times many locations to go to, good meals to find and sports activities to observe round

Rio: gosh, I ought to do mountain climbing…

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